In Domino Block, your goal is to match tiles based on the number of dots and strategically place them on the game board. You can play against 1, 2, or 3 opponents, making the game suitable for 2, 3, or 4 players in total. You can also choose a points goal to determine the length of the game, with options ranging from 100, 150, to 200 points. The first player to reach the selected score wins the match!